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The challenge of building user-friendly interfaces for computational biology

What you will learn

How to design user-friendly interfaces for computational biology

The challenges one face when designing user-friendly interfaces to computational biology

The challenges specific when it comes to innovation using mathematical models applied to medicine

Startups in healthcare

Target therapy

Description

Online reviews of the course

“Jorge Guerra Pires has created 2 courses that got 4 reviews which are generally positive. Jorge Guerra Pires has taught 25 students and received a 4.8 average review out of 4 reviews. Depending on the information available, Jorge Guerra Pires is a TRUSTED instructor.” coursemarks

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This course was officially launched on Thursday Morning Science. See Thursday Morning Science – 08/04/2021 on the YouTube channel

Università degli Studi dell’Aquila E-Learning. This presentation will give you a better idea whether the course is for you!

I have prepared also for you “Why I have launched “Innovating with Biomathematics””, see on our YouTube channel “Theoretical and Mathematical Biology”  You are going to have an overview of the course content and structure! 🙂

Please, let me know your thoughts on the matter, you can easily talk to me inside the course!

The course aims at bridging web developers, as I did on my postdoc, and biomathematician and life scientists, without regarding math; people get scared when see math.

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Short view of the course

When we create mathematical models to biology and medicine, an imperative challenge is how to make them available to the respective users/public. Software such as Matlab™ has been doing a nice work on that direction. However, it is my belief that anyone could use their expertise to create online platforms, for making their models into codes, and codes into user-friendly interfaces.  See an amazing discussion I did with Dr Jonathan Karr “Innovating with biomathematics | In Conversation with Jonathan Karr” on our YouTube channel  “Theoretical and Mathematical Biology”

On this course, I use an example for my most recent research period to make a point: user-friendly interface is imperative for making mathematical models available properly to the medical and biological sciences.  One of my concerns was JavaScript being powerful enough, it is! See my article “Why am I considering seriously JavaScript and Deep Learning? and I would suggest you to do so” on my profile on Medium.

In this course, I present an online platform that endows users with an interface designed to support medical doctors on applying computational biology to their decision process. This example is used to raise discussions and insights into the challenges of designing user-friendly interfaces to computational biology.

Moreover, I also talk about topics related to startups in healthcare and how it can support biomathematicians on their quest for making their models easily available to professionals with little, or even, no expertise on computational models. I truly believe the time is ripe for that since the technology I like to use, as an example, can easily be implemented machine learning based systems, see “MEAN + TensorFlow.js: a single language, a single data exchange format for machine learning based web applications!” on my profile on Medium.

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Join me on this endeavor with your lines of codes, and set of equations!

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About personalized medicine:  one aspect of personalized medicine is aiming at identifying specific targets for therapy considering the gene expression profile of each patient individually. The real-world implementation of this approach is better achieved by user-friendly bioinformatics systems for healthcare professionals.

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You may want to know:

This course is ideal for those that want to learn more about computational biology and innovative online systems based on computational biology.

This course is NOT ideal for those that want to learn about applications, the coding processes, I am planning to bring that on another courses! We already have one in Portuguese called “Mongoose, Test Driven Test-driven development, NestJS, Jest: Aprenda sobre o funcionamento do Mongoose focando em testes

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Keywords. Systems biology; target therapy; personalized medicine; user-friendly interface; web applications.

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Publications

Pires, J.G. (2022). Innovating with Biomathematics: the challenge of building user-friendly interfaces

for computational biology. Academia Letters, Article 5792.

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Main references:

´Pires JG. Alguns insights em Startups um novo paradigma para a tríplice aliança ciência, tecnologia e inovação: a novel paradigm for understanding the triple alliance of Science, Technology and Innovation. Rev. G&S [Internet]. 1º de fevereiro de 2020 [citado 4º de fevereiro de 2021];11(1):38 – 54.

Jorge Guerra Pires, Gilberto Ferreira da Silva, Thomas Weyssow, Alessandra Jordano Conforte, Dante Pagnoncelli, Fabricio Alves Barbosa da Silva, Nicolas Carels . “Galaxy and MEAN stack to create a user-friendly workflow for the rational optimization of cancer chemotherapy. “ Omics Technologies Toward Systems Biology. Special Issue.

The Startup Owner’s Manual: The Step-By-Step Guide for Building a Great Company. Book by Bob Dorf and Steve Blank

English
language

Content

Preliminares

Some initial words on the course
overview
miscellaneous: evaluating the course, feedback, and technical details of the cou

Introdução

overview
computer science + medicine = “neo-medicine”
The new ages, new challenges, the new endeavors: the human gemonme project
Systems biology, systems biomedicine, precision and personalized medicine: we st
Mathematical models, big data, and the future of computer simulations: the impor
Personalized medicine, target therapy, and user-friendly interfaces
From models to innovation
Have a nice course! enjoy the content!

Some insights into target therapyy

Initial words
introduction
Some definitions of target therapy
What is target therapy and why it is so imperative?
Example: finding hubs on gene regulatory networks

Evidence-based medicine

Some thoughts on evidence-based medicine

Frontend, the web application

Initial words
Frontend, subscription and business model
Some words on the backend (computational biology)
when the systems communicate

Some insights into startups on healthcare

Some initial words
Why startups in healthcare is so different from other types
Innovation risk vs. market/costumer risk
What is the difference between innovation risk vs. market/costumer risk?
innovation risk
Regarding innovation risk for computational biology. What is correct to assert
Innovation risk and target therapy
Risk of martket
Innovation risk and online platorms

User-friendly interfaces

User-friendly interfaces
Connecting the gears

Presenting my web application for discussion

Initial words
Some technical details
Demo from my web application for discussions
Closing lines

Presenting my web application for discussion, part II

Presenting the web application

Final remarks

Closing lines on the importance of user-friendly interfaces
I do not see any neurons here, only equations!
About the technologies used on the web application
What about business models?
I talked a lot about the difficulties, what about the facilities?
Final words
Testing your learning skills, and my teaching skills!