CRISPR Cas9 Technology
What you will learn
Learn How CRISPR-Cas9 system can modify DNA with greater precision than existing technologies.
Used to resolve mutations and to introduce site-specific therapeutic genes in human cells so that, correcting disease-causing mutations, and alleviate disease
Learning experience from experienced and certified Trainers.
Hands-on Projects to practice various concepts & tools, evaluated by our lead trainer.
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- Explore the revolutionary CRISPR-Cas9 system, understanding its biological origins as a bacterial immune defense and its adaptation as a powerful genome engineering tool.
- Master the intricate molecular machinery of CRISPR-Cas9, delving into guide RNA design, Cas9 nuclease specificity, and DNA repair pathways (NHEJ, HDR) dictating editing outcomes.
- Uncover diverse applications beyond human therapeutics, including its transformative potential in agricultural biotechnology for enhancing crop resilience and in livestock breeding for improved traits.
- Delve into advanced CRISPR technologies like Base Editing for precise single-nucleotide changes, and Prime Editing, offering greater versatility for targeted insertions, deletions, and all 12 base-to-base conversions.
- Learn to critically evaluate experimental design, including strategies for optimizing guide RNA efficiency, minimizing off-target effects, and selecting appropriate delivery methods for various cell types.
- Investigate the profound ethical, legal, and societal implications of germline editing, gene drives, and the accessibility of these powerful technologies, fostering responsible innovation.
- Gain insights into functional genomics and drug discovery, understanding how CRISPR-Cas9 enables high-throughput screening for gene function, target validation, and sophisticated disease model creation.
- Understand the rapidly evolving regulatory landscape surrounding genome editing, appreciating global efforts to balance scientific advancement with safety and ethical guidelines.
- PROS:
- Acquire in-demand skills in a rapidly expanding field, opening doors to careers in biotechnology, pharmaceuticals, and academic research.
- Engage with cutting-edge scientific developments, positioning yourself at the forefront of genetic engineering and its transformative impact on health, agriculture, and fundamental biology.
- Develop a comprehensive understanding of CRISPR technology, including its ethical dimensions and practical applications.
- Contribute to a future of precision medicine and sustainable solutions, leveraging the power of gene editing for global challenges.
- CONS:
- The field’s rapid evolution necessitates continuous learning beyond the course, as new variants, applications, and ethical considerations emerge frequently.
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